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Consequently, there is increased production of cytokines derived from T cells, such as TNF-, IFN-, IL-2, IL-17, and granulocyte-macrophage colony-stimulating factor, in the synovial fluid, leading to joint inflammation[40]
Over a median follow-up of 49.5 months, oral semaglutide reduced the risk of MACE by 14% compared to placebo (HR 0.86
