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Description
A single weigh-in can be misleading

Introduction Tirzepatide is a new medicine that helps treat diabetes and supports long-term weight management

doi: 10.1210/mend.15.9.0688
Several mechanisms explain why GLP-1 RAs reduce body weight: Central appetite suppression: GLP-1 receptors in the hypothalamus and brainstem alter hunger signalling and food reward

Three methods
