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have been prescribed a glucagonlike peptide1 drug for one or multiple indications, but 54% of users report affordability challenges.

The real problem seems to be retention

The result: Increased glucose-dependent insulin secretion Reduced glucagon release Better control of fasting & postprandial glucose Weight-neutral therapy with minimal risk of hypoglycemia A simple yet effective mechanism that plays a powerful role in modern diabetes management

This review article examines the translational evolution of glucagon-like peptide-1 receptor agonists (GLP-1RAs), tracing their progression from the discovery of exendin-4 in Gila monster venom to long-acting peptide analogues and the first orally delivered peptide therapy, oral semaglutide

A new lawsuit claims the manufacturers of Ozempic and Mounjaro do not adequately warn consumers of the drugs' "gastrointestinal side effects."
