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Early phase II studies in older adults with sarcopenia showed increases in lean mass and, in slower walkers, improvements in gait speed and 6-minute walk distance [62]

Nausea is the #1 reported side effect of these medications

The primary composite outcome of the study was the first occurrence of cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke

Be Wary of More Is Better Avoid Chronic High-Dose Protocols: Excessive dosing over prolonged periods risks compounding side effects such as insulin resistance and immune suppression