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Journal of Womens Health

Featured Snippet Answer : Based on current Phase 2 clinical trial data, Retatrutide achieved approximately 24% body weight reduction in 48 weeks, compared to semaglutides ~15% and tirzepatides ~22%

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The most commonly reported side effects include: Mild nausea or upset stomach Constipation or diarrhea Fatigue Headache Reduced appetite These symptoms are usually temporary and manageable, particularly when the dose is gradually increased under supervision

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