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NICE recommends that patients receive support from a multidisciplinary team delivering comprehensive weight management programs, emphasizing calorie restriction, increased physical activity, and behavioural interventions for long-term success by trained professionals [7]

The drug showed the potential to be given monthly, which Pfizer thinks would be more convenient than the currently weekly shots

Caution is advised in patients with a history of pancreatitis, and these medications should be avoided during pregnancy or discontinued well before planned conception (e.g., 2 months before planned pregnancy for semaglutide based on its half-life)

January 2021

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