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Semaglutide (Wegovy) reduced pain and improved physical function in patients with obesity and knee osteoarthritis, a randomized trial showed.Among 407 adults, the mean change in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain score from baseline to week 68 was -41.7 points in the semaglutide group and -27.5 points in the placebo group (P

Wegovy users report an average weight loss of 15-22% of body weight in clinical trials, with some patients losing more than 50 pounds