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Description
This design is important because it tries to answer a more nuanced question than a simple exposed-versus-unexposed comparison
Obes Surg (2015) 25:147481
The study was done with liraglutide (before semaglutide or tirzepatide were approved)
Tirzepatide (Mounjaro, Zepbound) is actually a dual GIP/GLP-1 receptor agonist
Another trial demonstrated a significant reduction in body weight with the use of semaglutide, with subjects losing up to 14.9% of their initial body weight over a period of 68 weeks
