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2003), whereas picrotoxin blocks both ionotropic GABA receptors and some isoforms of the glycine receptor

doi: 10.1039/D1FO02022F

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doi: 10.1212/WNL.0000000000208642
The synergistic activation of these three important receptors is capable to revert diet-induced obesity, cognitive impairment and T2D in mice models, warranting future human studies (201, 202)
