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"The person 14 months later is less healthy than they were when they started the drug," Cordani said

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If you are already taking a fiber supplement for GLP-1 support , consider reducing your fiber supplement dose during the first two weeks of Pendulum, then gradually restoring it once the probiotic side effects have resolved

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Co-formulation with low-dose blockers or the development of continuous-release implants, such as polymers co-loaded with semaglutide and bisoprolol, is currently under preclinical evaluation to mitigate tachycardia while preserving cardiovascular benefits [234, 335, 336]

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