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27 In the pancreas, GLP-1 receptor (GLP-1R) activation in islet cells promotes glucose-dependent insulin secretion from -cells, 28 inhibits glucagon release from -cells, and suppresses exocrine function via induction of pancreatic somatostatin

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In the future endocrinologists, psychiatrists, and neuroscientists will collaborate to develop integrated treatment approaches to target the unmet needs of patients whose illness may be seen at the interface between these medical specialties
