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The CuAAC reaction can be performed in a range of solvents, including mixtures of water and miscible organic solvents like alcohols, DMSO, DMF, and THF, while acetonitrile is typically avoided due to its strong coordinating ability toward Cu(I)

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What is the best treatment strategy for a 73-year-old male with type 2 diabetes, hypertension, hyperlipidemia, glaucoma, hypothyroidism, benign prostatic hyperplasia, possible Parkinson disease, who started sertraline 50 mg daily ten days ago for acute stress and now has paniclike symptoms, while taking canagliflozin, gabapentin, hydrochlorothiazide, insulin glargine (Lantus), levothyroxine, losartan, metformin, methocarbamol, omeprazole, rosuvastatin, and semaglutide?

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