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In a letter, the FDA said it needs more data to fully understand several possible risks tied to the drug, including heart and liver problems.

Recent advancementsincluding the approval of oral semaglutide (Rybelsus)have demonstrated the potential for effective oral peptide delivery, though such formulations still face significant pharmacokinetic and formulation-related challenges

New regulations taking effect on 1 October 2024 will remove compounded semaglutide-containing products from the pharmacy compounding exemption

Eric Topol: GLP-1 Drugs Reduce Substance Abuse Risk in Over 600,000 US Veterans / cancer, Eric Topol, GLP-1, OncoDaily, Oncology

Women in the study who were obese and taking GLP-1 weight loss medications were 30% less likely to develop breast cancer than other women.