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Weight Loss Drugs: Too Good to Be True

True GLP-1 agonists (semaglutide, tirzepatide) are prescription medications that directly bind the GLP-1 receptor

The engineered drug localized to lipid-rich plaque regions and CD11b/CD11c inflammatory cells, effectively suppressing inflammatory responses and enhancing cholesterol efflux ( By promoting cholesterol efflux and reducing foam-cell content within plaques, GLP-1RA therapy may decrease lipid core size and necrotic burden, thereby stabilizing the fibrous cap, lowering the risk of plaque rupture, and potentially reducing acute coronary events

The DCCT Research Group

Kim often keeps patients at lower doses longer rather than pushing quickly to the maximum dose