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EGFR-mediated activation of adipose tissue macrophages promotes obesity and insulin resistance

Drug-drug interactions and metabolic concerns Pharmacokinetic Interactions Anticoagulant and antiplatelet effects: The risk of bleeding increases by approximately 40%-70% among patients taking SSRIs, with the greatest elevations observed when these agents are combined with anticoagulants such as warfarin, antiplatelet agents like aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs)