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These adaptations position irisin as a promising therapeutic target for preventing metabolic disorders and optimizing exercise protocols

Cancer represents the main cause of death worldwide

Although, in the last 10 years, the use of GLP-1 RAs, especially semaglutide and liraglutide, has increased, its clinical implications and how it affects metabolic parameters have yet to be fully consolidated

Semaglutide works in the same way as a hormone produced in the gut by increasing the amount of insulin that the pancreas releases in response to food.

These medications belong to a class of glucagon-like peptide-1 (GLP-1) receptor agonists and are marketed under brand names such as Ozempic, Wegovy, Victoza, and Saxenda.GLP-1 is a naturally occurring hormone produced in the gut and brain that regulates appetite, blood suga