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(2025) (Open Access)

In patients with obesity (mean age 51.3 years, 65.6% women), semaglutide compared with non-GLP-1RA anti-obesity medications was associated with lower risk for incident CUD in patients with no prior history CUD (HR: 0.56, 95% CI: 0.420.75), and recurrent CUD diagnosis in patients with a prior history CUD (HR: 0.62, 95% CI: 0.460.84)

Risk of bias was assessed with ROBINS-I
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In the CIA mouse study, acarbose was orally administered from days -7 to 38 relative to type II collagen (CII) immunization
