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The OASIS 1 and 2 trials compared the therapeutic efficacy and clinical safety profile of once-daily oral semaglutide 50 mg versus placebo on overweight and obese participants without T2DM and both with and withoutT2DM, respectively
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World Health Organization
Once these fat cells become overfilled, they turn insulin resistant, meaning they stop accepting more energy (Bikman, 2020)
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