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It is important because it provides human biomarker-level support for the idea that GLP-1RA therapy influences redox-related physiology in parallel with its metabolic actions

Its thought to be more effective than semaglutide in helping people lose weight, according to research published in JAMA Internal Medicine in July 2024

Baggio et al., Plasma levels of DPP4 activity and sDPP4 are dissociated from inflammation in mice and humans, Nat

In 2023, semaglutide was the best-selling drug in the United States with nearly $14 billion in sales.1 There are an estimated 100 million obese adults in America, and an additional 37 million who may also be eligible to use medications like GLP-1s to manage chronic conditions

The rebrand of the Ozempic pill may reflect a broader shift in diabetes care toward GLP-1based therapies, with the FDA approving Foundayo, an oral GLP-1 receptor agonist from Eli Lily, in April 2026