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The semaglutide methylcobalamin compounds and tirzepatide methylcobalamin formulations use the more bioavailable form of B12

A few extra units at a low concentration may cause only mild additional nausea

Similarly, Ozempic is not licensed in the UK for weight management outside the context of diabetes, although a higher-dose formulation (Wegovy) has a specific licence for obesity treatment

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"Because diabetes and obesity aren't simple conditions, it's more effective to target several pathways at the same time," Saunders said