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Not staying at full therapeutic dose forever

Once acid reflux stabilizestypically within 4-6 weeks of starting or after dose adjustmentsmost patients resume their therapy progression without further digestive complications

This may help avoid rapid rises in blood glucose after meals

This changed after Dupr joined Roger Unger (figure 15), an American endocrinologist at the University of Texas Southwestern Medical Center in Dallas with a strong interest in glucagon and diabetes

Further research is needed to elucidate the precise mechanisms through which GLP-1R agonists exert their benefits and to establish their long-term safety and efficacy in diverse HFpEF populations