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Semaglutide: The Head-to-Head Data When directly compared in clinical trials, tirzepatide consistently demonstrates superior weight loss

First-line therapy for type 2 diabetes with sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists : a cost-effectiveness study

Beyond T2D and obesity, semaglutide was also applied for other indications such as cardiovascular disease, fatty liver, chronic kidney disease, all of which have progressed to Phase 3, expanding the influence of GLP-1RAs into more medical fields

Activation of the GLP-1 (glucagon-like peptide-1) receptor plays a central role in appetite and glucose regulation

6,8 To date, tirzepatide has achieved an unprecedented effect on improving Hemoglobin A1c (HbA1c) and body weight in T2DM patients