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Evidence Score: 9.2/10 | Best for: Endurance athletes and age-related energy decline MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide encoded within mitochondrial DNA that acts as a metabolic regulator

When you take Ozempic, it mimics the action of naturally occurring GLP-1, a hormone released by the intestines after eating

doi: 10.1016/j.cell.2005.07.007

The trial, involving 3,533 adults, started in June 2019 across 400 sites in 28 countries

Tirzepatide acts on two naturally occurring hormones in the body: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)