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Description
The Extra-Pancreatic Effects of GLP-1 Receptor Agonists: A Focus on the Cardiovascular, Gastrointestinal and Central Nervous Systems

106 Two additional clinical trials are being conducted to gather more data on adverse effects in different situations of liver injury, and a phase 2 trial investigating treatment effects for MASH with fibrosis based on histological assessment is ongoing (NCT05877547)

Decreased Appetite: Some individuals may experience a decrease in appetite while taking GLP-1 medications, which can be both a desired effect (supporting weight loss) and a potential side effect (leading to inadequate calorie intake)

They are used without the need for dose titration and give broadly similar HbA1c lowering efficacy to other oral antidiabetic agents

R., Sutter, D
