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In TNBC, methylation of certain promoter regions of key genes can alter gene expression, resulting in resistance to hormonal treatment and the promotion of more aggressive tumor characteristics

Department of Health and Human Services, said in a statement

doi: 10.1536/ihj.19-327 39 ZhouYHeXChenYHuangYWuLHeJ

169 Ghrelin also mediates insulinostatic actions even though human beta-cells do not express any known receptors for ghrelin, but a recent study discovered that the ghrelin receptor is expressed solely by delta-cells, implying that ghrelin dampens insulin secretion by inducing somatostatin release

Molecular Metabolism 5449458