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The ATTAIN-1 trial enrolled 3,127 participants and compared three doses of orforglipron (6, 12 and 36 mg) with placebo over 72 weeks

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Although rare, gallbladder problems, heart disease, hypertension, and worsening of diabetic retinopathy are serious conditions that require immediate attention from a healthcare provider

B12 supplementation is particularly relevant because GLP-1 agonists can reduce B12 absorption over time
