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55 Indeed, a more recent large meta-analysis confirmed that while GIPR variants may influence BMD, this does not necessarily translate to increased bone fracture risk

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Ben attributes this to several factors: Proven effectiveness in clinical trials and real-world use Social media and press coverage showcasing dramatic weight loss stories Advances in drug delivery, including long-acting formulations and oral options Expanding indications beyond diabetes to include obesity treatment Were in a situation where its the right molecule at the right time, Ben notes

The study 15 on cocaine use disorder only observed the effect of acute treatment with exenatide in a small set of patients, and thus more evidence is needed to understand the role of GLP-1 analogs in cocaine use disorder

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