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Pegsebrenatide was built from the start to act on microglia and astrocytes, the support cells whose chronic activation is now understood to drive a substantial portion of neurodegenerative pathology

We do not believe in one-size-fits-all programs

M.MarksS.HollandJ.OttawayN.SmileyD.DimarchiR.et al

Inhibiting phosphatidylinositol-3 kinase (PI3K) and ERK1/2 reduced HG's effects

Gastroenterology 115 : 13461352 Kim DY et al
