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Since muscle is a major energy utilizer 17,41 , minimizing muscle mass during caloric restriction can substantially reduce energy expenditure, thus sparing energy for the maintenance of other more critical organ systems 42,43,44

In particular, glucagon has firmly been demonstrated to enhance hepatic lipid metabolism, Hepatic GCGR agonism leads to upregulation of lipid catabolism pathways in the hepatocyte where a number of key regulatory transporters and enzymes facilitate beta oxidation of fatty acids (61)

Published evidence is too sparse to answer definitively

Vegetables: Vegetables like broccoli, carrots, and Brussels sprouts are not only low in calories and rich in nutrients but also high in fiber, potentially helping in the release of GLP-1 and regulating blood sugar levels