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Clinical trials have found that tirzepatide can produce greater average weight loss than semaglutide, in some cases by several additional percentage points

Activation of glucagon-like peptide-1 receptor promotes neuroprotection in experimental autoimmune encephalomyelitis by reducing neuroinflammatory responses

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Further studies are needed to determine how much of the benefit comes from weight loss versus the medication itself, Thompson noted

They also appear to offer protective benefits for vital organs including the heart, liver, and kidneys