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Description
The SOUL trial (2025), a large-scale, double-blind, placebo-controlled study, evaluated once-daily oral semaglutide in 9,650 patients with T2DM and established atherosclerotic cardiovascular disease, chronic kidney disease, or both

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Counseling Points * Take 3060 minutes before meals, preferably before breakfast

showed that it could reduce food intake, gastric emptying, body weight, liver function tests (LFTs), and glucose levels in a dose-dependent manner, thus improving hepatic insulin sensitivity and hepatic steatosis

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