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Gastrointestinal Issues Nausea Vomiting Constipation Abdominal discomfort Up to 50% of patients experience GI distress, especially at the start

Aronne LJ, Horn DB, le Roux CW, et al

Employers generally don't pay the list price for employee coverage, but even after various discounts, plan sponsors may pay a net price of around $569 to $664 a month per employee, according to estimates by the Institute for Clinical and Economic Review, making for a hefty bill

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Generic metformin at $4-10 per month is the cheapest option with metabolic benefits