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A multidisciplinary expert consensus published in Frontiers in Endocrinology recommends starting with osmotic laxatives (MiraLAX or magnesium) and only escalating to stimulant laxatives if osmotic options prove insufficient after 2-3 weeks of consistent use

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In a study in which GLP-1 peptide was infused, GLP-1 increased both cortical and medullary perfusion (40)

Schvarcz E, Palmer M, Aman J, Horowitz M, Stridsberg M, Berne C

Sources Novo Nordisk Ozempic: Using your Ozempic pen Mayo Clinic: Semaglutide (Subcutaneous Route) Side Effects FDA Access Data: Ozempic Label Pharmacy Times: InjectionSite Reactions and How to Manage Them (covers pain, swelling, itching, bruising, and prevention techniques) Cleveland Clinic Health Library: Semaglutide (Ozempic): How It Works & Side Effects (includes injectionsite itching, redness, rash) Journal of the American Academy of Dermatology: Dermatologic findings associated with semaglutide use: A scoping review (JAAD)