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Notably, although gallbladder disorders frequently manifest, advanced gastrointestinal complications such as intestinal obstruction and periprocedural aspiration, and emergent concerns regarding suicidality and ocular problems require further longitudinal studies to refine the usage guidelines for GLP-1 RAs in susceptible populations

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Both Ex-4 and Liraglutide were shown to enhance osteogenesis, suppress adipogenesis, and improve cell viability under stress conditions like hyperglycemia or inflammation

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