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Key takeaways Contrave and phentermine are FDA-approved prescription medications for weight loss

Both are compound patents, and both patents were filed around the same time

The most impactful findings to date come from the Phase 2 obesity trial (NCT04881760) , published in The New England Journal of Medicine in June 2023

This is not a fringe recommendation

Noticed to increase hunger, Tschp wondered if he could find a way to block ghrelin's action
