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GLP-1s delay how quickly our stomach digests food, leading to a feeling of fullness and satisfaction with smaller meal sizes

Despite similar half-lives, retatrutide (6 days), tirzepatide (5 days), and semaglutide (7 days) all support once-weekly dosing

Hanmi Pharmaceutical has started dosing patients in a Korean phase 3 trial of efpeglenatide for type 2 diabetes, adding a second late-stage path for the GLP-1 drug after filing it as an obesity treatment

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GLP-1 functions as an immune modulator because it controls macrophage polarization and T-cell functions [12,13]