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This phenotype is characterized by reduced maximal respiratory capacity, diminished basal oxygen consumption, and lower extracellular acidification ratesindicative of decreased lactate production and glycolytic activity ( Estrogens regulate the expression and activity of key enzymes in glycolysis, including hexokinase, phosphoglucoisomerase, phosphofructokinase, aldolase, glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase, 6-phosphofructo-2-kinase, and fructose 2,6-bisphosphatase ( 6 Do GLP-1 receptor agonists influence mitochondria and Alzheimers disease

Am J Gastroenterol 119(6):10281037 Osei SP, Akomaning E, Florut TF, Sodhi M, Lacy BE, Aldhaleei WA, Bhagavathula AS (2024) Gastrointestinal safety assessment of GLP-1 receptor agonists in the US: a real-world adverse events analysis from the FAERS database

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