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Experiment with timing during your first two weeks to find the schedule that feels most tolerable for your body

Additional doses of orforglipron will cost up to $399 if patients are paying cash

Phentermine may have a role in specific scenariossuch as short-term use (typically 12 weeks or less) in patients with no cardiac historybut evidence increasingly favors GLP-1 monotherapy as a first-line approach due to better safety margins and sustained weight loss

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As weight decreases, patients often find themselves enjoying increased energy and improved mobility, making it easier to embrace an active lifestyle