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Side effects are a common part of the treatment process, especially during the early weeks and during dose increases
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In practice combination therapies can deliver stronger glycemic control, more noticeable weight reduction, and a better patient response than using a single medication on its own, even when the goal seems the same

Also, dulaglutide-treated participants experienced dose-dependent weight loss, while the insulin glargine-treated group showed almost 1.28-kg weight gain
