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Description
This occurs through the activation of adenylyl cyclase, leading to increased intracellular levels of cyclic AMP (cAMP)
But GLP-1 is not right or safe for everyone

It has downstream consequences on metabolic rate, insulin sensitivity, long-term weight maintenance, and overall resilience

doi: 10.21037/apm.2019.10.01 2
Semaglutide , administered once weekly at doses up to 2.4 mg for weight management, lists headache as a 'common' side effect in its SmPC
