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The vascular hypometabolism hypothesis reframes dementia as a disorder of energy delivery, where chronic reductions in cerebral blood flow and glucose utilization precede and likely contribute to amyloid and tau pathology

A 2003 law bars Medicare's Part D drug benefit from covering any medication used for weight loss

It found that these drugs may slightly increase the chance of getting gallstones (cholelithiasis) and acid reflux (GERD)

Triple-hormone-receptor agonist retatrutide for obesity: a phase 2 trial

A 5 to 10 beat per minute increase that a 35-year-old barely notices might cause fatigue, exercise intolerance, or shortness of breath in a 65-year-old
