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As the use of GLP-1 drugs grow, some worry about widespread access.

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Here, we highlight the mechanisms linking T2DM and PD, as well as the links between insulin resistance (IR) and PD patients risk of developing cognitive deficits

Methods PAM amidation activity, postprandial GLP-1 levels, and the incretin effect were measured in carriers of PAM T2D-risk alleles and matched non-carriers from the Oxford Biobank in a prospective observational study and in Danish cohorts