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Description
There have been reports of gallbladder disease , including cholelithiasis (gallstones) and cholecystitis, possibly related to rapid weight loss
To test this hypothesis, a series of GIPR antagonist antibodies (GIPR-Ab) conjugated to GLP-1 peptides were created and investigated 34
There are also non-GLP-1 weight loss medications, such as Contrave (bupropion/naltrexone)

Scheen, A
106-OR: A First-in-Human Single Ascending Dose Study of Oxyntomodulin Analog LY3305677 in Healthy Subjects