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It is useful in treating dyskinesias, although it has been shown to be ineffective for the treatment of motor fluctuations

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doi: 10.1007/s12325-018-0868-9 12 PageMJMcKenzieJEBossuytPMBoutronIHoffmannTCMulrowCDet al

This is conferred by a targeted amino acid substitution at the 8th position, replacing alanine with glutamic acid, a modification also found in exenatide-based GLP-1 therapies
Weeks 24: The medication begins to reach a steady concentration
