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The result is hollowing under the eye that produces shadowing and the "tired" appearance even when well-rested
Resuming after prolonged interruption may require restarting at a lower dose to re-establish tolerance and minimise gastrointestinal side effects
The combination of semaglutide and regular alcohol may accelerate liver fat accumulation in susceptible individuals, though research is still emerging
Dose titration strategies: Gradual dose escalation represents the cornerstone of minimizing gastrointestinal adverse effects
Most patients report noticing these appetite changes within 24 to 72 hours, even before any scale movement occurs
