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As a highly selective GLP-1 receptor agonist, Semaglutide is designed to mimic the action of endogenous metabolic signaling hormones

95% CI 0.360.49), and TZD (aHR, 0.67

Cazzola 2024)

Most people lose 12 pounds per week on semaglutide, translating to 48 pounds monthly in the first phase of treatment
