glp-1 parkinson's disease lancet The Role of Glucagon-like Peptide-1

SURPASS-CVOT compared once-weekly tirzepatide with dulaglutide in adults with type 2 diabetes and high cardiovascular risk, showing a 9% relative risk reduction in MACE (HR 0.92, 95% CI 0.83 to 1.01)

Martchenko SE, Martchenko A, Biancolin AD, Waller A, Brubaker PL

3.3.2 Dulaglutide DUL is a long-acting GLP-1R agonist which can promote insulin secretion, inhibit gastric emptying, and reduce appetite

A: These medications may affect dopamine-related reward pathways in the brain that regulate craving and reinforcement behaviors

Published June 13, 2024 - More info The identification of genes that confer either extension of life span or accelerate age-related decline was a step forward in understanding the mechanisms of aging and revealed that it is partially controlled by genetics and transcriptional programs