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Exendin-4 (100 nM) decreased IFN- -induced signal transducer and activator of transcription-1 (STAT1), which is important for CXCL10 expression in the pancreatic beta-cell line, MIN6 cells, and human islets

Guo et al

Obesity status is calculated using self-reported height and weight rather than direct clinical measurement, which can produce underestimates

Persistent hyperglycemia can mediate hypoxic or ischemic injury, as well as elicit cardiomyocyte contractile dysfunction and the NF-B signaling pathway activation, thus inducing ER stress [152]

Working with a dietitian is important to ensure you are eating enough food and meeting all your nutrient needs. That said, Ozempic is not a replacement for healthy habits, says Singer