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J Clin Endocrinol Metab 108:24472469 Goldberg A, Graca S, Liu J et al (2024) Anti-obesity pharmacological agents for polycystic ovary syndrome: a systematic review and meta-analysis to inform the 2023 international evidence-based guideline

Bulk transcriptomic profiling revealed obesity-driven suppression of immune-related gene signatures in the tumor microenvironment (TME)including antigen presentationwhile sulindac treatment restored these signatures

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Similar results were observed in the groups subjected to TRF combined with resistance training (TRF + RT and TRF + CT), with improved performance (Figs