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Keywords: GLP-1 receptor agonists, preconception care, pregnancy safety Introduction Obesity prevalence has nearly tripled since 1975, with more than 650 million adults affected worldwide

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Semaglutide can cause nausea, vomiting, diarrhea, and constipation, especially at higher doses

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Clinical Trials Five clinical trials in diabetes have been undertaken (Surpass 14) [109,110,111,112,113] and the baseline characteristics are shown in Table 1